Mass Spectrometry of Phenylthiohydantoin (PTH) Amino Acids.
نویسندگان
چکیده
منابع مشابه
Rapid separation of phenylthiohydantoin amino acids: ambient pressure ion-mobility mass spectrometry (IMMS).
An electrospray ionization (ESI) ambient pressure ion-mobility spectrometer (APIMS) interfaced to an orthogonal reflector time-of-flight mass spectrometer (TOFMS) was evaluated for the first time as a detector for the identification of phenylthiohydantoin (PTH)-derivatized amino acids, the final products in the Edman sequencing process of peptides and proteins. The drift and flight times of the...
متن کاملMass Spectrometry of Amino Acids and Proteins
Likemostmatter (with the exception of, say, neutron stars), proteins and peptides are mostly made of nothing – an ephemeral cloud of electrons with very little mass surrounding tiny and very dense atomic nuclei that contain nearly all of themass (i.e., peptides and proteins aremade of atoms). Atoms havemass and the unit ofmass that is most convenient to use is called the atomic mass unit (abbre...
متن کاملChiral capillary electrophoresis-mass spectrometry of amino acids in foods.
In this work, the development of a new chiral capillary electrophoresis-mass spectrometry (CE-MS) method to separate D- and L-amino acids is shown. On-line coupling between CE and MS is established through an electrospray-coaxial sheath flow interface. Enantiomer separation is achieved by using a cheap, nonvolatile, chiral selector as beta-cyclodextrin in the background electrolyte (BGE) togeth...
متن کاملEffective Solvent Systems for Separation of PTH-Amino Acids on Polyamide Sheet
Two dimensional thin layer chromatography on polyamide sheets is a useful method for identification of PTH-amino acids which have very close Rf-values. The solvent systems described here are particularly effective and have an edge over other solvent systems used for the separation of PTH-amino acids. The solvent systems provide a clear separation of all PTH-amono acids except lle / Leu in a...
متن کاملMass Spectrometry of Non-protein Amino Acids: BMAA and Neurodegenerative Diseases
Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. The cause of these diseases is believed to be the interaction between genetic and environmental factors, synergistically acting with ageing. BMAA (β-methylamino-L-alanine) is...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1969
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.23-1679